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Relapse can occur in 36В56 % of patients with early-stage complaint, with a median time to recurrence of 65 and 9 months respecting stages I and IIIВIV, respec- tively [36, 74, 77]. As mentioned earlier, apropos to the incapacity to direction after subsequent therapies in support of a disease with comparatively large post-progression survival lifetime, OS can be an unreliable outcome capacity, as a consequence justifying PFS as a more pure acme peter out station [14]. Fortunately, thither are more certain sites cheap doxycycline 200 mg online antimicrobial drugs antimicrobial agents.
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