genetic and pathological connections between ALS and FTD are discussed in detail in this review with the purpose of describing a new ALS/FTD spectrum that will allow clinicians to diagnose these conditions and help researchers develop therapeutic strategies that target one or both conditions.The devastating ALSALS is a relatively common neurodegenerative condition affecting as much as 1:350 500 adults.10 Although its overall prevalence is low 2 in 100000
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