Could Covid vaccine be taken as a pill?

[geemong]

Could Covid vaccine be taken as a pill?

Right now, protection against Covid-19 comes via an injection. But in future, those vaccines could come from inhalers or even pills.

In a white, airy laboratory in Medicon Village, one of southern Sweden's largest science parks, chemist Ingemo Andersson holds up a thin, plastic inhaler, half the size of a matchbox.

Her team is hoping this tiny product could play a big role in the global fight against coronavirus allowing people to take powdered versions of future vaccines at home.

"It's easy and it's really cheap to produce," says Johan Waborg, CEO of the firm, which usually makes inhalers for patients with asthma.

"You just remove a little plastic slip and then the vaccine inhaler is activated and you just put it in your mouth, take a deep breath and inhale."

The company, Iconovo, is collaborating with an immunology research start-up in Stockholm, ISR, which has developed a dry-powder vaccine against Covid-19.

It uses manufactured Covid-19 virus proteins (unlike Pfizer, Moderna and Astra Zeneca which use RNA or DNA that code for these proteins), and can withstand temperatures of up to 40C.

That's a major contrast to the conditions needed to store the current commonly available coronavirus vaccines approved by the World Health Organization (WHO), which are all in liquid form.

They have to be kept in tough glass vials in temperatures as low as -70C, before being transferred to fridges, or they they lose effectiveness - known as the "cold chain".

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